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  Cyproheptadine and Tricholine Citrate Syrup

Cyproheptadine & Tricholine Citrate

SYRUP PRESENTATION:
Each 5 ml contains:

Cyproheptadine IP 2 mg
Tricholine Citrate 275 mg
Sorbitol 70% IP (Non-Crystallis ing) Q.S

This composition having Cyproheptadine and Tricholine Citrate help revives appetite. Cyproheptadine is a serotonin and histamine antagonist with sedative property. It finds clinical application in stimulating the appetite and growth. The appetite stimulating effect of cyproheptadine is probably a consequence of serotonin antagonism. It antagonizes the satiety stimulating effects of serotonin on the satiety center. Weight gain has been observed with cyproheptadine can be attributed to an interference with regulation of the secretion of growth hormone. Tricholine citrate in this combination contains three molecules of choline. Clinical interest in choline centers on its lipotropic action & its utility in the treatment of fatty infiltration and cirrhosis of liver. Choline converts fat into phospholipids like, lecithin, which is essential to biomembrane structure and its function. Lecithin is also a major component of high density lipoprotein (HDL), and is used to mobilize cholesterol from cell membrane.

It stimulates appetite, provides effective hepato-protective action, ensures weight gain, and enhances protein synthesis. It is indicated in Hepatobiliary disorders associated with Anorexia resulting in Weight loss

MAO inhibitors prolong and in tensify the anticholinergic effects of antihistamines. This combination may have additive effects with alcohol and other CNS depressants like, hypnotics, sedatives, tranquilizers and anti-anxiety agents.

• Drowsiness
• Dry mouth
• Confusion
• Ataxia

This combination is contraindicated in individuals:

• Hypersensitivity to any ingredient of the formulation
• In Bulimia nervosa (Where patient takes excess food)