Vitamin D3 Drops

Indications:- Rickets & Osteomalacia

DROP PRESENTATION:
Each 5 ml contains:

Each 5ml (Teaspoonful )contains:
Vitamin D3 IP 400/800 IU

Description

This drops of vitamin D3 helps to get rid of bone disorders such as rickets and osteomalacia in children. As, the age and dark skin leads to restricted exposure to sunlight thus this result in deficiency of vitamin D.

LICENSED INDICATION

  • It helps in the metabolism of calcium and phosphorus
  • It helps to build strong bones and teeth’s
  • It helps the absorption of calcium in muscles for contraction and relaxation, for flexibility.
  • It promotes the growth and development of kids
  • It enhances the function of immune system

Mode of Action

Vitamin D acts on the receptors present in the small intestine which enhances the absorption of calcium and phosphorus. It also stimulates the receptors present in osteoblasts which stimulates the nuclear factor KB which helps the maturation of bones for reabsorption of calcium and phosphorus.

Pharmacokinetics

Absorption- It is absorbed orally from the small intestine
Protein Binding- It is 50-80% bound to proteins
Metabolism- It undergoes hydroxylation and converted into 25-hydroxycalciderol
Excretion- It is excreted via bile and feces

Drug Interaction

  • Phenobarbital
  • Phenytoin
  • Atorvastatin

ADVERSE EFFECT

  • Nausea
  • Vomiting
  • Poor appetite
  • Stomach-ache
  • Constipation
  • Diarrhoea

CONTRAINDICATION

  • Contraindicated in sarcoidosis
  • Contraindicated in Kidney stones
  • Contraindicated in kidney disease

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